Establishment of the remineralization-promoting treatment and the caries-preventive protocol by novel fissure sealant

2013 Fiscal Year Final Research Report

• Project/Area Number: 23792525
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Social dentistry
• Research Institution: The Nippon Dental University
• Principal Investigator: SHIMAZU Kisaki 日本歯科大学, 生命歯学部, 講師 (80582254)
• Project Period (FY): 2011-04-28 – 2013-03-31
• Keywords: シーラント / S-PRGフィラー / フッ素リリース・リチャージ / イオン徐放 / 脱灰・再石灰化

Research Abstract

We aimed to evaluate the caries-preventive effect of a fissure sealant containing surface reaction-type pre-reacted glass ionomer (S-PRG) filler. For the sealant containing S-PRG filler, high amount of Sr and B ions was detected, and a considerable amount of fluoride was released after a recharge with a high concentration of fluoride. Moreover, the S-PRG filler-containing sealant bonded by self-etching primer maintained the enamel surface integrity and inhibited enamel demineralization. In addition, the sealant had a higher bond strength on both untreated enamel and enamel subsurface lesions than the conventional resin-based sealants bonded by acid etching. These findings suggest that sealants containing S-PRG filler enhance the enamel demineralization-inhibiting effect and the remineralization-promoting effect for long-term dental care.

Research Products

• [Journal Article] S-PRGフィラー含有シーラントの齲蝕予防効果の検討 (2013)
  • Author(s): 島津貴咲
  • Journal Title: 小児歯誌 Volume: 52(3) Pages: 347-352
  • URL: http://www.jspd.or.jp/contents/gakkai/journal/j_journal.html
• [Journal Article] Evaluation of the caries-preventive effect of three orthodontic band cements in terms of fluoride release, retentiveness, and microleakage (2013)
  • Author(s): Shimazu K, Ogata K, Karibe H
  • Journal Title: Dent Mater J. Volume: 32(3) Pages: 376-380
  • DOI: 10.4012/dmj.2012-283
  • Peer Reviewed
• [Journal Article] Caries-preventive effect of fissure sealant containing surface reaction-type pre-reacted glass ionomer filler and bonded by self-etching primer (2012)
  • Author(s): Shimazu K, Ogata K, Karibe H
  • Journal Title: J Clin Pediatr Dent Volume: 36(4) Pages: 343-347
  • URL: http://pediatricdentistry.metapress.com/home/main.mpx
  • Peer Reviewed
• [Presentation] S-PRG溶出液の口腔微生物に対する抗菌効果 (2014)
  • Author(s): 島津貴咲,高橋幸裕,小口莉代,古西清司,苅部洋行
  • Organizer: 第52回日本小児歯科学会
  • Place of Presentation: 東京,品川区立総合区民会館
  • Year and Date: 20140516-17
• [Presentation] Evaluation of the caries-preventive effect of three orthodontic band cements (2013)
  • Author(s): Shimazu K, Ogata K, Karibe H
  • Organizer: 92th International Association for Dental Research
  • Place of Presentation: Washington State Convention Center 800, Seattle, Washington, USA
  • Year and Date: 20130320-23
• [Presentation] 歯磨きによる唾液酸緩衝能の変化 (2013)
  • Author(s): 横山美世子,朝倉美希,大野智,角掛愛,中村元一,巻祐太,水沼詩葉,加藤雄一,島津貴咲
  • Organizer: 第28回日本小児歯科学会関東地方会大会・総会
  • Place of Presentation: 神奈川,神奈川歯科大学
  • Year and Date: 2013-10-27
• [Presentation] Caries-preventive effect of novel resin-based fissure sealant (2012)
  • Author(s): Karibe H, Shimazu K, Ogata K
  • Organizer: 65th annual session of American Academy of Pediatric Dentistry
  • Place of Presentation: San Diego Convention Center, San Diego, California, USA
  • Year and Date: 20120524-27
• [Presentation] 新規S-PRGフィラー含有シーラントの有用性フッ素リリース能とリチャージ能の評価 (2012)
  • Author(s): 島津貴咲,小方清和,苅部洋行
  • Organizer: 第50回日本小児歯科学会
  • Place of Presentation: 東京,東京国際フォーラム
  • Year and Date: 20120512-13
• [Presentation] S-PRGフィラー含有シーラントの齲蝕予防効果の検討 (2012)
  • Author(s): 島津貴咲
  • Organizer: 第50回日本小児歯科学会,学術賞・奨励賞受賞講演
  • Place of Presentation: 東京,東京国際フォーラム
  • Year and Date: 2012-05-13
• [Remarks] 日本歯科大学生命歯学部小児歯科学講座 ホームページ
  • URL: http://www.ndu.ac.jp/~pedo/index.html