Fundamental research on prognostic prediction of pressure ulcers

2016 Fiscal Year Final Research Report

• Project/Area Number: 23792562
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Fundamental nursing
• Research Institution: Teikyo University
• Principal Investigator: Arai Naoko 帝京大学, 医療技術学部, 准教授 (10432303)
• Project Period (FY): 2011-04-28 – 2017-03-31
• Keywords: 褥瘡 / アセスメント / MMP-9 / BMP-6

Outline of Final Research Achievements

In this study, in order to utilize the biopolymer to evaluate the wound leading to prediction of the pressure ulcer prognosis, we considered proteins considered to be involved in wound healing contained in exudate collected from the wound of pressure ulcer. As a result, it was possible to find a relationship between detection amounts of matrix metalloprotease-9 and bone morphogenetic protein-6 and some of the DESIGN-R scores. From these results, it was shown that MMP-9 and BMP-6 are effective polymeric markers for judging the qualitative state of wounds and can be used as an evaluation tool.

Free Research Field

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