2012 Fiscal Year Final Research Report
Investigation on neural mechanisms of the effect of touch using an indicator of cardiovascular responses to painful stimuli
| Project/Area Number |
23792575
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Fundamental nursing
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| Research Institution | Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology |
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Principal Investigator |
WATANABE Nobuhiro 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (00540311)
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| Project Period (FY) |
2011 – 2012
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| Keywords | タッチ / 痛み / 循環 / 脊髄 / μ-オピオイド受容体 |
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| Research Abstract |
The present study examined the effect of gentle cutaneous stimulation (touch) and its mechanism using heart rate responses to noxious heat stimulation as an indicator in anesthetized rats. We found that touch using a soft elastomer brush inhibited heat-induced heart rate responses. Additionally, the inhibitory effect of touch on heart rate responses was abolished by blocking spinal μ-opioid receptors.
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