2012 Fiscal Year Final Research Report
Revelation of linkage between the change of cortical neural activity and the induction mechanism of plasticity during motor learning with the newest optical methods
| Project/Area Number |
23800071
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | National Institute for Basic Biology |
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Principal Investigator |
MASAMIZU Yoshito 基礎生物学研究所, 光脳回路研究部門, 特別協力研究員 (90608530)
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| Project Period (FY) |
2011 – 2012
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| Keywords | カルシウムイメージング / 光子励起顕微鏡 / 運動学習 |
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| Research Abstract |
I performed two-photon calcium imaging in L2/3 and L5 of the mouse primary motor cortex during a few weeks of a self-initiated lever-pull task, identifying L2/3 and L5 based on the cortical depth of the imaging plane. During motor learning, increasing firing rate of neurons was frequently observed in L5 than L2/3
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