2012 Fiscal Year Final Research Report

Elucidation of molecular mechanism for maintaining chromosome alignment regulated by novel protein, CAMP

Research Project

Project/Area Number	23870001
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Cell biology
Research Institution	Tohoku University
Principal Investigator	ITOH Go 東北大学, 加齢医学研究所, 助教 (60607563)
Project Period (FY)	2011 – 2012
Keywords	細胞・組織 / 生物・生体工学 / プロテオーム
Research Abstract	Accurate chromosome segregation requires proper chromosome alignment at equatorial region in metaphase. Recently, we identified novel molecule, CAMP, which plays an important role in a maintaining of chromosome alignment (EMBO J, 2011). In this study, we examined a molecular mechanism for the maintaining of chromosome alignment mediated by CAMP. Therefore, I identified a CAMP interacting protein during mitosis and then assessed a relationship between CAMP and the interacting protein involved in maintainingof chromosome alignment.

(4 results)