2012 Fiscal Year Final Research Report
Elucidation of immunological mechanisms in swine selected for resistance to Mycoplasmal pneumonia
| Project/Area Number |
23880004
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied animal science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 抗病性 / ブタ / 免疫 |
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| Research Abstract |
The immunophenotype of a novel swine line genetically selected to reduce the incidence of pulmonary lesions caused by MPS was analyzed in this study. The reactivity of peripheral blood mononuclear cells stimulated with bacteria-associated component was lower in MPS selected animal rather than conventional pigs, and the reactivity of lymphocyte to MPS vaccine sensitization in vivo was also lower in the MPS selected pigs. Meanwhile, the induction of IFN-g was higher in MPS selected pigs after vaccine sensitization. These immunological characteristics are considered to be important for the reduction of MPS lesions
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Research Products
(4 results)
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[Journal Article] Immunological characterization of peripheral blood leukocytes using vaccine for mycoplasmal pneumonia of swine (MPS) in swine line selected for resistance to MPS2013
Author(s)
Shimazu T, Borjigin L, Katayama Y, LiM,Satoh T, Watanebe K, Kitazawa H, Roh S, Aso H, Kazuo K, Suda Y, Sakuma A, Nakajo M, K.Suzuki
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Journal Title
Animal Science Journal
Volume: (In press)
DOI
Peer Reviewed
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[Presentation] Changes in peripheral blood leukocytes in swine selected line for resistance to MPS2012
Author(s)
T.Shimazu, J.Riku, Y.Katayama, M.Li, T.Sato, H.Kitazawa, H.Aso, K.Katoh, Y.Suda, A.Sakuma, M.Nakajoh, K.Suzuki
Organizer
The 63rd Annual Meeting of the EAAP
Place of Presentation
Bratislava, Slovakia
Year and Date
2012-08-29
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