2012 Fiscal Year Final Research Report
First step toward ascertaining bacteriocin productionfrom lactic acid bacteria in animal intestinal tract
| Project/Area Number |
23880019
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Okayama University |
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Principal Investigator |
ARAKAWA Kensuke 岡山大学, 大学院・環境生命科学研究科, 助教 (50609930)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 乳酸菌 / バクテリオシン / 抗菌ペプチド / Lactobacillus gasseri |
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| Research Abstract |
Most strains of Lactobacillus gasseri, a predominant in human small intestinal tract, produce an antibacterial peptide, namely bacteriocin “gassericin T”. In this study, we demonstrated that gassericin T is produced from 9 genes in the chromosome of its producer, and that it consists of two simple peptides associated with each other in solution. These results would contribute to future research on the effect of bacteriocins on host-gut microbiota and health.
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