2012 Fiscal Year Final Research Report
Selective activation of carboxylic acids by developing novel catalysts
| Project/Area Number |
23890034
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SHIMIZU Yohei 東京大学, 大学院・薬学系研究科, 助教 (60609816)
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| Project Period (FY) |
2011 – 2012
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| Keywords | カルボン酸 / ボロン酸 / 触媒 |
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| Research Abstract |
We found that aldol reaction using carboxylic acids as substrates could be proceeded under mild condition by activating with an equivalent of borane. In addition, the usage of dummy ligands could tune the reactivity and selectivity.
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