2012 Fiscal Year Final Research Report
The study of TGFβ associated novel biomarker that could detect high risk premalignant lesion.
| Project/Area Number |
23890080
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 口腔癌 / 前癌病変 / CD109 / 免疫組織化学 / 診断マーカー |
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| Research Abstract |
Immunohistochemical analysis using paraffin embedded samples of oral dyisplasia showed CD109 positive rate of high-risk group was significantly higher than that of control group. In immunohistochemical analysis of tongue squamous cell carcinoma (TSCC), a positive relation was existed between Ki-67 and CD109 expression in well or moderately differentiated TSCC including CIS.
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[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma'2012
Author(s)
Sumitaka Hagiwara, Noriyuki Yamamoto, Hiroki Furue, Hiroki Sakakura, Toshio Shigetomi, Yoshiki Murakumo, Hideharu Hibi, Masahide Takahashi, Minoru Ueda.
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Journal Title
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Volume: Accepted 3
URL
Peer Reviewed
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