2012 Fiscal Year Final Research Report
Analysis of bone regeneration by mesenchymal stem cells from jaw bone and application for the treatment of jaw cleft
| Project/Area Number |
23890136
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 顎骨由来 MSC / 口唇裂・口蓋裂 / 骨再生 / 再生医学 |
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| Research Abstract |
A collection and a primary cell culture even little steady of mesenchymal stem cell (MSC) derived from jaw bone became possible. No significant differences in the cell proliferation and the differentiation in osteoblasts between MSCsfrom iliac bone and jaw bone. Moreover, any significant differences were not shown between the experimental side, jaw bone origin MSC mixed with the carbonated hydroxyapatite particles and the control side, iliac origin MSC with the carbonated hydroxyapatite particles in vivo experiment for bone regeneration on the beagle dogs.
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