2012 Fiscal Year Final Research Report
The Research of Sex Hormonal Influence on the Meibomian Gland and the Ocular Surface Epithelium
| Project/Area Number |
23890181
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
SUZUKI Tomo 京都府立医科大学, 医学研究科, 客員講師 (30613236)
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| Project Period (FY) |
2011 – 2012
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| Keywords | ドライアイ / マイボーム腺 / 性ホルモン / マイボーム腺機能不全 |
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| Research Abstract |
In the present study, the methods of collection for meibomian gland secretion (meibum) without contamination were reevaluated and the analysis of fatty acid (FA) composition of meibum was conducted. In healthy volunteers meibum was composed of 40% saturated and 60% unsaturated FAs. In unsaturated Fas branched FAs were dominant and in unsaturated FAs monounsaturated was the major component. In premenstrual women the FA composition changed according to their menstrual cycle.
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