2012 Fiscal Year Final Research Report
Apatite-coated hyaluronan for bone regeneration
| Project/Area Number |
23890196
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tohoku University (2012)
Kyushu Dental College (2011) |
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Principal Investigator |
TANAKA Kenko 東北大学, 大学院・歯学研究科, 助教 (00610049)
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| Project Period (FY) |
2011 – 2012
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| Keywords | ヒアルロン酸 / アパタイト / 骨芽細胞 / 骨造成 |
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| Research Abstract |
ALP activity and the expression of bone-related molecules increased on ACH. At 3 weeks, ACH showed bone formation the most, and were observed newly bone surrounding osteopontin immunostained osteoblasts. ACH promoted greater differentiation ofosteoblast-like cells compared to AS in vitro, and showed an excellent newly bone formation in vivo.
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