2012 Fiscal Year Final Research Report
Characterization of immunoregulation by Th17 cell on Periodontal disease model
| Project/Area Number |
23890217
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nihon University |
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Principal Investigator |
KOBAYASHI Ryoki 日本大学, 松戸歯学部, 助手(専任扱) (10609085)
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| Project Period (FY) |
2011 – 2012
|
| Keywords | 感染症 / 免疫学 / 歯周疾患 / TH17 / 口腔粘膜 |
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| Research Abstract |
In order to clarify the mechanism of Periodontal diseases, we characterized the immunoregulatory effect by Th17 cells in the inflamed gingiva of mice with alveolar bone resorption. In this study, we employ Aggregatibacter actinomycetemcomitansone, one of the higher risk factors for induce of inflammation to gingiva and alveolar bone loss.
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Research Products
(4 results)
