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2023 Fiscal Year Annual Research Report

Adaptation of marine zooplankton to climate change conditions: a multi-omic study of molecular mechanisms.

Research Project

Project/Area Number 22H03795
Allocation TypeSingle-year Grants
Research InstitutionOkinawa Institute of Science and Technology Graduate University

Principal Investigator

ラスカム ニコラス  沖縄科学技術大学院大学, ゲノム・遺伝子制御システム科学ユニット, 教授 (70724087)

Project Period (FY) 2022-04-01 – 2025-03-31
KeywordsBioinformatics / Genomics / Climate change / Marine biology / Plankton
Outline of Annual Research Achievements

In the past 12 months, we have published a paper on the observation of large-scale genomic rearrangements between Oikopleura dioca populations, and demonstrated that the Okinawa population forms a distinct sub-species of Oikopleura, even though their appearance is near-identical to the mainland Japanese populations.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

The project has progressed as expected, with gene expression and chromatin status measurements for Okinawa and Osaka populations completed. We are now analysing the data, in order to understand the similarities and differences in the regulatory wiring of the two populations, at normal and at different environmental conditions.

Strategy for Future Research Activity

In the final year of project, we will focus on analysing the data, performing validation experiments, and writing a paper to be submitted in late 2024/early 2025.

  • Research Products

    (14 results)

All 2024 2023 Other

All Journal Article (9 results) (of which Int'l Joint Research: 9 results,  Peer Reviewed: 6 results,  Open Access: 9 results) Presentation (4 results) (of which Int'l Joint Research: 3 results) Remarks (1 results)

  • [Journal Article] Extreme genome scrambling in cryptic Oikopleura dioica species2024

    • Author(s)
      C.Plessy, M.J.Mansfield, A.Bliznina, A.Masunaga, C.West, Y.Tan, A.Liu, J.Grasic, M.S. del Rio Pisula, G.Sanchez-Serna, M.Fabrega-Torrus, A.Ferrnandez-Roldan, V.Roncalli, P.Navratilova, E.M.Thompson, T.Onuma, H.Nishida, C.Canestro, N.M.Luscombe
    • Journal Title

      Cold Spring Harbor Lab

      Volume: 34 Pages: 426-440

    • DOI

      10.1101/gr.278295.123

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] RNA polymerase II-associated proteins reveal pathways affected in VCP-related amyotrophic lateral sclerosis2023

    • Author(s)
      Mahmoud-Reza Rafiee, Sara Rohban, Karen Davey, Jernej Ule, Nicholas M Luscombe
    • Journal Title

      OXFORD Academic BRAIN

      Volume: 146 Pages: 2547-2556

    • DOI

      10.1093/brain/awad046

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clipplotr-a comparative visualization and analysis tool for CLIP data2023

    • Author(s)
      Anob M Chakrabarti, Charlotte Capitanchik, Jernej Ule, Nicholas M Luscombe
    • Journal Title

      RNA

      Volume: 29 Pages: 715-723

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A computationally-enhanced hiCLIP atlas reveals Staufen1-RNA binding features and links 32023

    • Author(s)
      Anob M Chakrabarti, Ira A Iosub, Flora CY Lee, Jernej Ule, Nicholas M Luscombe
    • Journal Title

      OXFORD University Press

      Volume: 51 Pages: 3573-3589

    • DOI

      10.1093/nar/gkad221

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Nf-core/clipseq - a robust Nextflow pipeline for comprehensive CLIP data analysis2023

    • Author(s)
      Charlotte West, Charlotte Capitanchik, Chris Cheshire, Nicholas M Luscombe, Anob Chakrabarti, Jernej Ule
    • Journal Title

      Wellcome Open Research

      Volume: 8 Pages: 286

    • DOI

      10.12688/wellcomeopenres.19453.1

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale2023

    • Author(s)
      Charlotte Capitanchik, Sam Ireland, Alex Harston, Chris Cheshire, D Marc Jones, Flora CY Lee, Igor Ruiz de los Mozos, Ira A Iosub, Klara Kuret, Rupert Faraway, Oscar G Wilkins, Rahul Arora, Martina Hallegger, Miha Modic, Anob M Chakrabarti, Nicholas M Luscombe, Jernej Ule
    • Journal Title

      bioRxiv, Cold Spring Harbor Lab

      Volume: - Pages: -

    • DOI

      10.1101/2023.08.22.544179

    • Open Access / Int'l Joint Research
  • [Journal Article] Poised PABP-RNA hubs implement signal-dependent mRNA decay in development2023

    • Author(s)
      Jernej Ule, Miha Modic, Klara Kuret, Sebastian Steinhauser, Rupert Faraway, Emiel van Genderen, Flora Lee, Igor Ruiz de Los Mozos, Ziga Vicic, Jona Novljan, Derk ten Berge, Nicholas Luscombe
    • Journal Title

      Research Gate

      Volume: - Pages: -

    • DOI

      10.21203/rs.3.rs-3227673/v1

    • Open Access / Int'l Joint Research
  • [Journal Article] scRNA-sequencing in chick suggests a probabilistic model for cell fate allocation at the neural plate border2023

    • Author(s)
      Alexandre P Thiery, Ailin Leticia Buzzi, Eva Hamrud, Chris Cheshire, Nicholas M Luscombe, James Briscoe, Andrea Streit
    • Journal Title

      Elife Sciences Publications Limited

      Volume: 12 Pages: e82717

    • DOI

      10.7554/eLife.82717

    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains2023

    • Author(s)
      Harold P Hodgins, Pengsheng Chen, Briallen Lobb, Xin Wei, Benjamin JM Tremblay, Michael J Mansfield, Victoria CY Lee, Pyung-Gang Lee, Jeffrey Coffin, Ana T Duggan, Alexis E Dolphin, Gabriel Renaud, Min Dong, Andrew C Doxey
    • Journal Title

      Nature Communications

      Volume: - Pages: 5475

    • Open Access / Int'l Joint Research
  • [Presentation] Genomic scramble in marine plankton2024

    • Author(s)
      Nicholas M. Luscombe
    • Organizer
      OIST x Kyudai Joint Symposium Series 1
  • [Presentation] Targeted haplotype-aware assembly of complex regions and small genomes with NOVOLoci2023

    • Author(s)
      Nicolas Dierckxsens
    • Organizer
      14th AGW International Workshop
    • Int'l Joint Research
  • [Presentation] Population Genomic Study Reveals Local Adaption Signals in Oikopleura dioica around Ryukyu Islands2023

    • Author(s)
      Jiashun Miao
    • Organizer
      Tohoku International Symposium "Past, Present, and Future of the Marine Environment and Ecosystems"
    • Int'l Joint Research
  • [Presentation] The species concept in environmental and genetic studies: the case of the zooplankton Oikopleura dioica going from global to cryptic2023

    • Author(s)
      Charles Plessy
    • Organizer
      Tohoku International Workshop “Pathways Towards an Integrated Understanding of the Marine Environment and Marine Ecosystems”
    • Int'l Joint Research
  • [Remarks] Species identity crisis in the genome community

    • URL

      https://www.oist.jp/news-center/news/2024/5/9/oikopleura-who-species-identity-crisis-genome-community

URL: 

Published: 2024-12-25  

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