2023 Fiscal Year Annual Research Report
Adaptation of marine zooplankton to climate change conditions: a multi-omic study of molecular mechanisms.
Project/Area Number |
22H03795
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Allocation Type | Single-year Grants |
Research Institution | Okinawa Institute of Science and Technology Graduate University |
Principal Investigator |
ラスカム ニコラス 沖縄科学技術大学院大学, ゲノム・遺伝子制御システム科学ユニット, 教授 (70724087)
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Project Period (FY) |
2022-04-01 – 2025-03-31
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Keywords | Bioinformatics / Genomics / Climate change / Marine biology / Plankton |
Outline of Annual Research Achievements |
In the past 12 months, we have published a paper on the observation of large-scale genomic rearrangements between Oikopleura dioca populations, and demonstrated that the Okinawa population forms a distinct sub-species of Oikopleura, even though their appearance is near-identical to the mainland Japanese populations.
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Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The project has progressed as expected, with gene expression and chromatin status measurements for Okinawa and Osaka populations completed. We are now analysing the data, in order to understand the similarities and differences in the regulatory wiring of the two populations, at normal and at different environmental conditions.
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Strategy for Future Research Activity |
In the final year of project, we will focus on analysing the data, performing validation experiments, and writing a paper to be submitted in late 2024/early 2025.
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[Journal Article] Extreme genome scrambling in cryptic Oikopleura dioica species2024
Author(s)
C.Plessy, M.J.Mansfield, A.Bliznina, A.Masunaga, C.West, Y.Tan, A.Liu, J.Grasic, M.S. del Rio Pisula, G.Sanchez-Serna, M.Fabrega-Torrus, A.Ferrnandez-Roldan, V.Roncalli, P.Navratilova, E.M.Thompson, T.Onuma, H.Nishida, C.Canestro, N.M.Luscombe
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Journal Title
Cold Spring Harbor Lab
Volume: 34
Pages: 426-440
DOI
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale2023
Author(s)
Charlotte Capitanchik, Sam Ireland, Alex Harston, Chris Cheshire, D Marc Jones, Flora CY Lee, Igor Ruiz de los Mozos, Ira A Iosub, Klara Kuret, Rupert Faraway, Oscar G Wilkins, Rahul Arora, Martina Hallegger, Miha Modic, Anob M Chakrabarti, Nicholas M Luscombe, Jernej Ule
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Journal Title
bioRxiv, Cold Spring Harbor Lab
Volume: -
Pages: -
DOI
Open Access / Int'l Joint Research
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[Journal Article] Poised PABP-RNA hubs implement signal-dependent mRNA decay in development2023
Author(s)
Jernej Ule, Miha Modic, Klara Kuret, Sebastian Steinhauser, Rupert Faraway, Emiel van Genderen, Flora Lee, Igor Ruiz de Los Mozos, Ziga Vicic, Jona Novljan, Derk ten Berge, Nicholas Luscombe
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Journal Title
Research Gate
Volume: -
Pages: -
DOI
Open Access / Int'l Joint Research
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[Journal Article] Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains2023
Author(s)
Harold P Hodgins, Pengsheng Chen, Briallen Lobb, Xin Wei, Benjamin JM Tremblay, Michael J Mansfield, Victoria CY Lee, Pyung-Gang Lee, Jeffrey Coffin, Ana T Duggan, Alexis E Dolphin, Gabriel Renaud, Min Dong, Andrew C Doxey
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Journal Title
Nature Communications
Volume: -
Pages: 5475
Open Access / Int'l Joint Research
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