Development of highly sensitive magnetic field sensing system for the purpose of cell tissue functional evaluation

2014 Fiscal Year Final Research Report

• Project/Area Number: 24240080
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical systems
• Research Institution: Nagoya University
• Principal Investigator: UCHIYAMA Tsuyoshi 名古屋大学, 工学(系)研究科(研究院), 准教授 (00203555)
• Co-Investigator(Kenkyū-buntansha): NAKAYAMA Shinsuke 名古屋大学, 医学研究科, 准教授 (30192230)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 細胞組織 / 生体磁気 / 心磁図 / 脳磁図

Outline of Final Research Achievements

We developed highly sensitive magneto-impedance sensor by use of pulse current excitation method and achieved pT sensitivity, which is necessary for cell tissue magnetic field evaluation.　Magnetic fields generated by spontaneous electrical activity in the mouse and guinea pig tissue preparation were measured by use of the developed highly sensitive magneto-impedance sensor. We　confirmed that that detection magnetic signal is closely correlated with electrical signal and synchronized with electrical signal at the tissue surface. We analyzed current distribution in the cell tissue based on the experimental results. We concluded that the developed magneto-impedance sensor system is useful for cell tissue bio-magnetic measurement as well as for Magnetocardiography (MCG) and Magnetoencephalography (MEG).

Free Research Field

電子工学