The mechanisms for deterioration of thermoregulatory responses in older people and the counter measure against their heat illness

2014 Fiscal Year Final Research Report

• Project/Area Number: 24240089
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sports science
• Research Institution: Shinshu University
• Principal Investigator: NOSE Hiroshi 信州大学, 学術研究院医学系, 教授 (40128715)
• Co-Investigator(Kenkyū-buntansha): KAMIJO Yoshi-ichiro 信州大学, 学術研究院医学系, 講師 (40372510) ; OKAZAKI Kazunobu 大阪市立大学, 都市健康・スポーツ研究センター, 准教授 (70447754) ; HIGUCHI Keiichi 信州大学, 学術研究院医学系, 教授 (20173156) ; TANIGUCHI Shun'ichiro 信州大学, 学術研究院医学系, 教授 (60117166)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: スポーツ生理学 / 運動生理学 / 体温調節能 / 血液量 / インシュリン

Outline of Final Research Achievements

We examined any merits of the supplementation of a mixture of carbohydrate and protein during exercise training. First, we divided older men into 2 groups; carbohydrate + protein (Pro-CHO) and carbohydrate (CHO) supplementation groups. After 2-mo training, we found that thermoregulatory responses more improved with more increases in plasma volume and albumin content in Pro-CHO than CHO but arterial blood pressure decreased in both groups. Second, we divided older women into 3 groups; control (CNT), low (L-Pro-CHO), and high carbohydrate + protein (H-Pro-CHO) supplementation during interval walking training. After 5-mo training, we found that muscle strength, plasma volume, and inflammatory genes methylation increased more in H-Pro-CHO than CNT. In addition, the inter-individual variation of renal Na+ reabsorption rate in response to plasma insulin concentration during OGTT was smaller in H-Pro-CHO than in CNT. Thus, the supplementation might enhance the benefits of exercise training.

Free Research Field

スポーツ医科学