Development of selective therapeutic techniques by excitation of molecular vibration using mid-infrared lasers

2015 Fiscal Year Final Research Report

• Project/Area Number: 24241029
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Quantum beam science
• Research Institution: Osaka University
• Principal Investigator: AWAZU Kunio 大阪大学, 工学(系)研究科(研究院), 教授 (30324817)
• Co-Investigator(Kenkyū-buntansha): ISHII Katsunori 大阪大学, 大学院工学研究科, 助教 (20512073) ; HAZAMA Hisanao 大阪大学, 大学院工学研究科, 准教授 (70437375)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: レーザー医療 / レーザー生体相互作用 / 中赤外レーザー / 低侵襲治療 / 疾患選択的治療 / 量子カスケードレーザー

Outline of Final Research Achievements

It was found that selective removal of atherosclerotic plaque and carious dentin is possible using mid-infrared laser at the wavelengths of 5.75 and 5.8 μm, respectively. Endoscopic treatment system for early gastric cancer was developed using a carbon dioxide laser, and in-vivo porcine experiment was succeeded. Quantitative diagnosis system for atherosclerosis was developed using near-infrared light at a wavelength range of 1200 nm. Accurate measurement technique for optical properties of biological tissues was developed to precisely estimate the light propagation in the biological tissue.

Free Research Field

レーザー医工学、生体組織光学