2014 Fiscal Year Final Research Report
Development of a method for simultaneous recordings of single channel dynamics and currents
| Project/Area Number |
24249013
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General physiology
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
IWAMOTO Masayuki 福井大学, 医学部, 助教 (40452122)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 蛋白質 / 1分子動態計測 |
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| Outline of Final Research Achievements |
Prior to realizing simultaneous recordings of single-molecular dynamics and currents we tried to increase time-resolution of the dynamics measurementin this project. We intorduced a X-ray focusing mirror and a spectrum measurement system to the sychrotorn facility(SPring8). The time resolutions of the dynamics measurements became to be in a sub-millisecond level, which is equivalent to that of single channel current measurement. And the X-ray radiation damages of the ion channel proteins were decreased by using the spectrum measurement system. These advances of the method will lead to the development of simultaneous measurement system in near future.
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| Free Research Field |
生理学・生物物理学
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