2014 Fiscal Year Final Research Report
Spatiotemporal control mechanisms of neural circuit formation
| Project/Area Number |
24300116
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | Chiba University |
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Principal Investigator |
SAITO Tetsuichiro 千葉大学, 医学(系)研究科(研究院), 教授 (00202078)
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| Co-Investigator(Kenkyū-buntansha) |
MUROYAMA Yuko 千葉大学, 大学院医学研究院, 特任講師 (20422248)
SATO Tatsuya 千葉大学, 大学院医学研究院, 助教 (00568222)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 遺伝子 / 細胞・組織 / 神経科学 / 脳・神経 / 発生・分化 / 脊髄 / 神経細胞 / 電気穿孔法 |
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| Outline of Final Research Achievements |
Neural circuit formation requires fine spatiotemporal control of each step, such as neuronal differentiation and axonal projection. We have developed a new method in which gene expression is turned on in an aimed portion of the mouse nervous system in vivo. Mice that have a defect in a restricted part of neural circuits and a specific behavioral disorder have been efficiently obtained.
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| Free Research Field |
神経科学
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