Physical therapy to promote the recovery from muscle injury in rat

2014 Fiscal Year Final Research Report

• Project/Area Number: 24300191
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Nagoya University
• Principal Investigator: KAWAAKAMI Keisuke 名古屋大学, 医学(系)研究科(研究院), 准教授 (60195047)
• Co-Investigator(Kenkyū-buntansha): SOKABE Masahiro 名古屋大学, 医学系研究科, 教授 (10093428)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 骨格筋 / 筋損傷 / 機械刺激 / 超音波 / ラット / リハビリテーション

Outline of Final Research Achievements

To evaluate the effect of ultrasound and stretching on recovery from muscle injury, changes in muscle force production and myogenic gene expressions were investigated in an LC-induced muscle injury mode of rat. We established the LC-induced muscle injury model, whose injury was histologically confirmed to be equivalent. The results show that ultrasonic stimulation and stretching added once after muscle injury on the TA effectively promotes recovery from muscle injury according to histological and physiological evaluation. Additionally, during recovery from muscle injury the activation of muscle satellite cells early after muscle injury is suggested to be involved.

Free Research Field

理学療法学