Construction of capsule-like coorporative molecular recognizing structures from saccharide-recognizing host molecules

2015 Fiscal Year Final Research Report

• Project/Area Number: 24350066
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Functional materials chemistry
• Research Institution: University of Toyama
• Principal Investigator: ABE Hajime 富山大学, 大学院医学薬学研究部(薬学), 准教授 (10324055)
• Co-Investigator(Renkei-kenkyūsha): INOUYE Masahiko 富山大学, 大学院医学薬学研究部(薬学), 教授 (60211752)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 糖認識 / ホスト分子 / カプセル型分子 / 集積構造 / フェノール / ピリジン / 繊維状構造

Outline of Final Research Achievements

By applying artificial host molecules as parts, higher-order structures such as capsule-like and fibril structures have been built. Coordinative groups were introduced on the ortho positions of triphenolic host molecules, and the product tridentates were treated with a Pd(II) precursor to give M3L2-type capsule-like complex, which showed host ability. Macrocyclic host molecules consisted of 2,6- and 3,6-pyridylene rings were observed to self-associate by pi-stacking, and AFM images showed fibril structures. Tricationic derivative incorporated melamine with self-aggregate into cotton-like structure.

Free Research Field

ホスト・ゲスト化学