Hollow microcapsules fabricated from ultrasonically generated microbubbles of cyanoacrylate instant adhesive

2014 Fiscal Year Final Research Report

• Project/Area Number: 24360066
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: Yamagata University
• Principal Investigator: MAKUTA TOSHINORI 山形大学, 理工学研究科, 准教授 (40451661)
• Co-Investigator(Renkei-kenkyūsha): TAKAHASHI Ichiro 山形大学, 大学院理工学研究科, 名誉教授 (50007217) ; FUKAMI Tadanori 山形大学, 大学院理工学研究科, 准教授 (70333987)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: マイクロバブル / 超音波 / マイクロカプセル / 画像診断システム / ドラッグデリバリー

Outline of Final Research Achievements

We developed a new method for the fabrication of hollow microcapsule blowing the vapor of moisture curing polymer into water as microbubbles. The hollow microcapsules are composed of cyanoacrylate, a biocompatible material used for adhesion to human tissue such as skin, blood vessels, and organs. Moreover these are less than 10 um in diameter, which is smaller than a blood capillary (approximately 10 um). Therefore, with their stable polymer shells, the hollow microcapsules are possible ultrasound contrast agents, and are expected to be generated at low cost on the medical frontline.

Free Research Field

流体工学