Development of a Blood Pump for Implantable Right Ventricular Assist Device

2014 Fiscal Year Final Research Report

• Project/Area Number: 24360075
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: TSUKIYA Tomonori 独立行政法人国立循環器病研究センター, 研究所, 室長 (00311449)
• Co-Investigator(Kenkyū-buntansha): HORIGUCHI Hironori 大阪大学, 基礎工学研究科, 准教授 (60314837)
• Co-Investigator(Renkei-kenkyūsha): MIZUNO Toshihide 国立循環器病研究センター, 研究所, 室長 (40426515) ; TAKEWA Yoshiaki 国立循環器病研究センター, 研究所, 室長 (20333405) ; TSTSUMI Eisuke 国立循環器病研究センター, 研究所, 部長 (00216996) ; TSUJIMOTO Yoshinobu 大阪大学, 基礎工学研究科, 教授 (50112024)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 人工心臓 / 血液 / 数値流体力学 / 遠心ポンプ

Outline of Final Research Achievements

A implantable centrifugal blood pump was developed as a blood pump for an implantable right ventricular assit device, that are required to make a mechanical circulatory support for severe heart failure. The centrifugal blood pump was designed with the aid of computational fluid dynamics software, and a prototype was manufactured. The basic performances as a blood pump for right ventricular assist was confirmed, while a minor modification was needed in the design of the hydrodynamic bearings that is one of the key components to obtain sufficient antithrombogenicity for a long-term use. The modified pump demonstrated that the amount of broked blood cells by passing through the pump was within a clinically acceptable range.

Free Research Field

流体工学