Study of integrated optical biosensors unsing silicon technology

2015 Fiscal Year Final Research Report

• Project/Area Number: 24360136
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Electron device/Electronic equipment
• Research Institution: Hiroshima University
• Principal Investigator: Yokoyama Shin 広島大学, ナノデバイス・バイオ融合科学研究所, 教授 (80144880)
• Co-Investigator(Kenkyū-buntansha): IKEDA TAKESHI 広島大学, 大学院先端物質科学研究科, 助教 (10505754)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: バイオセンサー / Siリング共振器 / 差動検出 / Siフォトニック結晶共振器 / 前立腺特異抗原 / 温度安定性

Outline of Final Research Achievements

The purpose of this research is to develop the compact and high sensitivity biosensors using Si photonics. Differential Si ring resonators and photonic crystal (PhC) resonators were investigated. For the differential ring resonators, the method to obtain a constant sensitivity was proposed and the practical sensitivit of 0.5 ng/ml was achieved for the prostate specific antigen. Concerning the PhC resonators, it was found that the cavity type resonator has the superior sensitivty than defect type. Spot size converter, which enhances the coupling constant more than 30 times than previous, was developed. Thermal change mechanism for the resonance wavelength was studied and it was revealed that the intrinsic refractive index change is dominant than that of mechanical deformation.

Free Research Field

半導体工学