Development of an ecological and economical urine sensing system for diabetic disease screening

2015 Fiscal Year Final Research Report

• Project/Area Number: 24360141
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Electron device/Electronic equipment
• Research Institution: Osaka Institute of Technology
• Principal Investigator: Mitsuaki Yano 大阪工業大学, 工学部, 教授 (40200563)
• Co-Investigator(Kenkyū-buntansha): KOIKE Kazuto 大阪工業大学, 工学部, 准教授 (40351457) ; SASA Shigehiko 大阪工業大学, 工学部, 教授 (50278561) ; TSUTSUI Hiroshi 大阪工業大学, 工学部, 教授 (00351453) ; OMATU Shigeru 大阪工業大学, 工学部, 教授 (30035662)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 先端機能デバイス / 計測工学 / 電子デバイス・機器

Outline of Final Research Achievements

The target of this study is to develop ecological and economical urine sensing systems for diabetic disease screening. For this purpose, we developed a solution-gate field-effect transistor (SGFET) made of a Ta2O5/ZnO film on a glass substrate, and immobilized proton receptors, globulin aptamers, or glucose oxidase molecules on the gate electrode. These SGFET sensors were demonstrated to be able to detect the concentrations of protons, globulins, and β-D glucose in solution with enough sensitivity and detection range required for the screening. We also developed the MEMS technology to integrate these SGFETs into a healthcare chip, original ceramic gas sensors to check the characteristics of diabetic odor in urine or exhaled breath, and a prototype expert system of an electronic nose using a layered neural network.

Free Research Field

半導体デバイス