Development of "Displome" for industrial applications of cell surface display

2014 Fiscal Year Final Research Report

• Project/Area Number: 24360342
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Biofunction/Bioprocess
• Research Institution: Kobe University
• Principal Investigator: AKIHIKO Kondo 神戸大学, 工学(系)研究科(研究院), 教授 (40205547)
• Co-Investigator(Kenkyū-buntansha): TANAKA Tsutomu 神戸大学, 大学院工学研究科, 准教授 (90436551) ; OGINO Chiaki 神戸大学, 大学院工学研究科, 准教授 (00313693) ; YAMADA Ryosuke 神戸大学, 自然科学系先端融合研究環, 助教 (00313693) ; MATSUMOTO Takuya 神戸大学, 自然科学系先端融合研究環, 助教 (00313693)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: バイオリファイナリー

Outline of Final Research Achievements

The development of efficient utilization of renewable biomass resources is one of the important issues to overcome the environmental / energy problems. We have developed cell surface display system, which is a powerful tool due to endowing the biomass degrading activity on the host cells. Here, we developed comprehensive approaches to develop cell surface display applicable for other useful microorganisms. As a results, several kinds of anchor proteins have been developed and enables them to providing biomass degrading activity. In addition, using cell surface engineered microorganisms, direct production from biomass was achieved.

Free Research Field

生物化学工学