2014 Fiscal Year Final Research Report
Fluctuation in the size of species-specific repetitive DNA of hominoids: quantitative analysis by comparative genomics
| Project/Area Number |
24370098
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Physical anthropology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
KOGA Akihiko 京都大学, 霊長類研究所, 教授 (80192574)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SHIMADA Atsuko 東京大学, 大学院理学系研究科, 助教 (20376552)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | ゲノム / 反復配列 / サテライトＤＮＡ / ヒト / 霊長類 / 分子進化 |
|---|
| Outline of Final Research Achievements |
Repetitive sequences occupy large fractions of their host genomes, and their organization is thought to undergo considerable changes in evolutionary processes. The purpose of the present study was to reveal actual changes that had occurred in the evolution of hominoids. Main results and their significance were: (1) alpha satellite DNA has been replaced by another repetitive DNA in a gibbon genome, (2) a novel transposon was, and can be in the future, formed and expanded in hominoid genomes, and (3) the evolutionary origin of the higher-order repeat structure of alpha satellite DNA is older than that commonly postulated.
|
| Free Research Field |
分子進化学
|
