2014 Fiscal Year Final Research Report
Analysis of the mechanism for non-HR type necrosis of Arabidopsis infected by a virus
| Project/Area Number |
24380025
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plant pathology
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| Research Institution | Hokkaido University |
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Principal Investigator |
MASUTA Chikara 北海道大学, (連合)農学研究科(研究院), 教授 (60281854)
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| Co-Investigator(Kenkyū-buntansha) |
TAKESHITA Minoru 九州大学, 大学院農学研究院, 助教 (00304767)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | Cucumber mosaic virus / catalase / necrosis |
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| Outline of Final Research Achievements |
We analyzed the molecular mechanism by which Cucumber mosaic virus (CMV) induces necrosis on inoculated leaves of Arabidopsis. We could show direct evidence of the protein-protein interaction between the 2b protein of CMV (2b) and host catalase (Cat3). The stability of the 2b-Cat3 complex seems to be regulated by cellular proteasome; the more stable the complex is, the more rapidly it is degraded. For the host plant, Cat3 may function as an anti-CMV factor that can interfere with the function of 2b.
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| Free Research Field |
植物病理学
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