2015 Fiscal Year Final Research Report
Development of a control method of protein function within cell using photodegradable nanoparticles and its medical applications
| Project/Area Number |
24390007
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Kato Masaru 東京大学, 薬学研究科(研究院), 准教授 (30332943)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
|
| Keywords | ナノ粒子 / タンパク質 / 細胞 |
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| Outline of Final Research Achievements |
To examine the cellular reaction, we developed photodegradable nanoparticles that penetrate cellular membrane with encapsulated molecule and released the encapsulated molecule by light stimulus. We compared the cellular response after releasing the different amount of protein within cell using the nanoparticles. Our results indicated that the nanoparticles is a useful tool for the study of cellular reaction.
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| Free Research Field |
分析科学
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