2014 Fiscal Year Final Research Report
Molecular Species of phosphoinositides and their functions
| Project/Area Number |
24390067
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
General medical chemistry
|
|---|
| Research Institution | Akita University |
|---|
Principal Investigator |
SASAKI Junko 秋田大学, 医学(系)研究科(研究院), 准教授 (30333371)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
NAKANISHI Hiroki 秋田大学, 大学生体情報研究センター, 助教 (10466740)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 細胞内シグナル伝達 / イノシトールリン脂質 |
|---|
| Outline of Final Research Achievements |
We established the sensitive method for measuring phosphoinositides (PIs) by mass spectrometry, and found that various PIs molecular species were exist in cells. Through the analyses of the cells with overexpression or knockout of PIs metabolizing enzymes, it was suggested that each PIs species might have different cellular functions.
|
| Free Research Field |
脂質生化学
|
