2014 Fiscal Year Final Research Report
An evaluation of environmental pollutant exposure using cell survival signaling and development of simple detection system
| Project/Area Number |
24390159
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAWAMOTO Toshihiro 産業医科大学, 医学部, 教授 (60177748)
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| Research Collaborator |
MORITA Kentaro
SONG Yuan
NAKANISHI Tsukasa
HE Cuiying
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 環境汚染物質 / 粒子サイズ / NF-κB / LPS |
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| Outline of Final Research Achievements |
Exposure to elevated concentrations of particulate matter (PM), air pollution has been implicated as a risk factor for our health. These pollutants include a mineral, a chemical substance and microbes such as bacteria. In this communication, we showed that administration of PM or exposure of chemicals to mice modified immune responses. Furthermore, different size of particles showed different modification in immune responses. It will open the door for new assessment for detection of exposure of air pollutants.
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| Free Research Field |
免疫学
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