A study on brain mechanisms of emotional control and restoring mechanisms to their disturbance

2014 Fiscal Year Final Research Report

• Project/Area Number: 24390284
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Hiroshima University
• Principal Investigator: SHIGETO Yamawaki 広島大学, 医歯薬保健学研究院, 教授 (40230601)
• Co-Investigator(Kenkyū-buntansha): OKAMOTO Yasumasa 広島大学, 大学院医歯薬保健学研究院, 准教授 (70314763) ; YOSHINO Atsuo 広島大学, 大学院医歯薬保健学研究院, 助教 (90633727) ; NAKAO Takashi 広島大学, 大学院教育学研究科, 准教授 (40432702) ; MORINOBU Shigeru 高知大学, 医学部, 教授 (30191042) ; YAMASAHITA Hidehisa 広島大学病院, 講師 (50294591)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 精神生理学

Outline of Final Research Achievements

We examined the brain mechanisms of emotional control and restoring mechanisms to their disturbance in healthy controls, depression, and pain disorder. We conducted various cognitive-emotional tasks and functional magnetic resonance imaging in healthy controls or pain disorder, and examined the comparison of brain activities between pre and post cognitive behavior therapy (CBT) in patients with depression. These studies have shown that the pathology of depression and pain disorder or the restoring brain mechanism of depression modulated by CBT might be associated with the specific brain regions such as medial prefrontal cortex, anterior cingulate cortex, and insula.

Free Research Field

精神医学