Investigation of state-of-the art functional MR imaging supporting fertility sparing and minimal-invasive operation

2014 Fiscal Year Final Research Report

• Project/Area Number: 24390291
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: TOGASHI Kaori 京都大学, 医学(系)研究科(研究院), 教授 (90135484)
• Co-Investigator(Kenkyū-buntansha): FUJIMOTO Koji 京都大学, 医学研究科, 助教 (10580110) ; KATAOKA Masako 京都大学, 医学研究科, 助教 (10611577) ; KIDO Aki 京都大学, 医学研究科, 助教 (80595710)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: MRI / 低侵襲治療 / 生殖医療

Outline of Final Research Achievements

We visualized uterine peristalsis both sagittal and coronal images. Each direction of the image may have its merit and demerit for evaluating the peristalsis. In addition, automatic evaluation system has been promoted. Non-contrast enhanced MRA of the uterine artery could indicate the difference between pre and after menopausal state, which correspond to the previous reports by Doppler US. As for cervical cancer, treatment effect of neoajuvant chemotherapy was well correlated with the tumor size rather than ADC value obtained from DWI and quantitative values from perfusion images. Regarding the event free survival and overall survival, mean ADC value was an independent biomarker for event free survival in patients with SCC in the multivariate analysis.

Free Research Field

画像診断学