A novel device for drug delivery to the posterior segment of the eye

2015 Fiscal Year Final Research Report

• Project/Area Number: 24390392
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Hokkaido University
• Principal Investigator: Ishida Susumu 北海道大学, 医学(系)研究科(研究院), 教授 (10245558)
• Co-Investigator(Kenkyū-buntansha): OZAWA Yoko 慶應義塾大学, 医学部, 講師 (90265885)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: ドラッグデリバリーシステム / レニン・アンジオテンシン系

Outline of Final Research Achievements

We evaluated the safety of conjunctival rings (CR), a novel device for drug delivery to the posterior segment of the eye. Our data demonstrated that CR is safe for use in vivo. The use of CR has the advantage of avoiding several side effects that are associated with the existing implant devices, since removing the device from the ocular surface easily discontinues the drug therapy. Therefore, CR could be a new drug delivery device and safe approach in the treatment of posterior segment diseases such as age-related macular degeneration, diabetic macular edema and uveitis.

Free Research Field

眼科学