2015 Fiscal Year Final Research Report
Studies on geographical distribution and genomic diversity of a new pathogenic Entamoeba species in Asia
| Project/Area Number |
24406013
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Tokai University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Seiki 慶應義塾大学, 医学部, 講師 (70112688)
KOMIYAMA Tomoyoshi 東海大学, 医学部, 准教授 (60439685)
MAKIUCHI Takashi 東海大学, 医学部, 助教 (80587709)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 原虫 / Entamoeba nuttalli / マカク / 疫学 / 遺伝子多様性 / ゲノム / 人獣共通感染症 / アジア |
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| Outline of Final Research Achievements |
Entamoeba nuttalli, a new pathogenic species, was detected in fecal samples from rhesus macaques in Nepal and Myanmar, long-tailed macaques in Thailand, toque macaques in Sri Lanka, and Tibetan macaques in China. On the other hand, E. histolytica was not found in these samples. More than 80 strains of E. nuttalli were cultured successfully. Diversity of serine-rich protein genes and tRNA-linked short tandem repeat sequences was correlated with geographical distribution of host macaques. Draft genome sequence of E. nuttalli P19-061405 strain was determined.
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| Free Research Field |
寄生原虫学
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