Investigation of possible mechanism for regulation of cerebral blood flow during exercise

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500478
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Fusional brain recording science
• Research Institution: Hosei University
• Principal Investigator: HIURA Mikio 法政大学, スポーツ健康学部, 教授 (10327918)
• Co-Investigator(Kenkyū-buntansha): NARIAI Tadashi 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 (00228090) ; ISHII Kenji 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (10231135)
• Co-Investigator(Renkei-kenkyūsha): TAKAHASHI Katsumi 神奈川工科大学, 創造工学部, 教授 (30267637)
• Research Collaborator: MUTA Akitaka 東京医科歯科大学, 医歯(薬)学総合研究科
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 陽電子放出断層撮像法 / 脳血流 / 運動

Outline of Final Research Achievements

We investigated changes in regional cerebral blood flow (rCBF) during cycling ergometer which was continued at low intensity. Main findings of this research project are; 1) Distribution of increased rCBF during exercise was differed between the onset and a later phase of exercise. Afferent neural impulse from working muscles in lower limbs and central command would have a role in regulation of rCBF during exercise. 2) rCBF reduced after exercise secession by 16 %, approximately, in several regions such as posterior cingulate gyrus. 3) The similar type of exercise as evaluated in the PET study induced changes in regional oxygennation which were distinct from the tendency of those in rCBF.

Free Research Field

脳計測科学