2014 Fiscal Year Final Research Report
The application to cancer vaccine of SSF that mimics pulmonary surfactant
Project/Area Number |
24500527
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Biomedical engineering/Biological material science
|
Research Institution | Musashino University (2013-2014) The University of Tokushima (2012) |
Principal Investigator |
MIZUNO Dai 武蔵野大学, 薬学研究所, 講師 (70380061)
|
Co-Investigator(Renkei-kenkyūsha) |
KIDO Hiroshi 徳島大学, 疾患酵素学研究センター, 特任教授 (50144978)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Keywords | 肺サーファクタント / 粘膜免疫 / ワクチン / 生体機能材料 |
Outline of Final Research Achievements |
The cellular immunity inducing effect of SSF, a synthetic adjuvant that mimics pulmonary surfactant, were shown in this study. Nasal inoculation of vaccine and SSF induced IgG2a antibody, IFN-γ secreting T cell, and cytotoxic T cell. SSF is assumed to be a mucosal adjuvant that useful for cancer vaccine therapy.
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Free Research Field |
医歯薬学
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