Rehabilitation and the markers for its evaluation in rheumatoid arthritis

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500592
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Nagasaki University
• Principal Investigator: ORIGUCHI Tomoki 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (90295105)
• Co-Investigator(Kenkyū-buntansha): KAWASHIRI Shinya 長崎大学, 医歯薬学総合研究科(医学系), 助教 (20457576) ; OKITA Minoru 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (50244091)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: リハビリテーション / 関節リウマチ / サイトカイン / 神経ペプチド / 超音波検査

Outline of Final Research Achievements

In rehabilitation of rheumatoid arthritis patients, exercise therapy, gymnastics, and physical therapy were performed. CRP,DAS28-CRP,and IL-6 were improved by exercise therapy. Tender joint number, DAS-CRP, and IL-6 were improved by gymnastics. Tender joint number, pain VAS, and mHAQ were improved by physical therapy. In excercise therapy, a significant correlation was seen in IL-6 and a change of DAS28-CRP, and it was suggested that IL-6 was a useful marker for evaluation of excercise therapy. Althou there was not seen a significant improvement of the articular lesion in joint sonography, the observation was useful for monitering that rehabilitation was performed safely.

Free Research Field

リハビリテーション