Involvement of temperature receptors in neurogenic bladdder

2015 Fiscal Year Final Research Report

• Project/Area Number: 24500594
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Kagoshima University
• Principal Investigator: Yoshida Akira 鹿児島大学, 医歯学域医学部・歯学部附属病院, 講師 (40347109)
• Co-Investigator(Kenkyū-buntansha): IKEDA Satoshi 北海道大学, 大学病院, 准教授 (00343369) ; KAWAHIRA Kazumi 鹿児島大学, 医歯(薬)学総合研究科, 客員研究員 (20117493) ; OHWATASHI Akihiko 鹿児島大学, 医歯域医学系, 准教授 (30295282)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 温熱 / 排尿反射 / ラット / シストメトリー

Outline of Final Research Achievements

We investigated the effect of warming on the micturition reflex in conscious and decerebrate rats. Intravesical warming decreased pressure threshold for indicing micturition, resting pressure, closing peak pressure, and increased bladder compliance. On the other hand, skin warming at S1 dermatome level decreased closing peak pressure, increased resting pressure, and had no effect on pressure threshold for indicing micturition and bladder compliance. These results suggest that intraｖesical warming and skin warming exert effects on the micturition reflex by different mechanisms.

Free Research Field

リハビリテーション医学