3D analysis of muscle metabolism during exercise

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500799
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Sports science
• Research Institution: Tokyo Medical University
• Principal Investigator: KIME Ryotaro 東京医科大学, 医学部, 講師 (90366120)
• Co-Investigator(Kenkyū-buntansha): NIWAYAMA Masatsugu 静岡大学, 電子工学研究所, 准教授 (40334958) ; KATSUMURA Toshihito 東京医科大学, 医学部, 教授 (80214352) ; MURASE Norio 東京医科大学, 医学部, 講師 (10317894) ; OSADA Takuya 東京医科大学, 医学部, 講師 (60297281)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 筋酸素動態 / 近赤外線分光法 / 磁気共鳴分光法 / 不均一性 / エネルギー代謝

Outline of Final Research Achievements

This study used two-dimensional 31Phosphorus Chemical Shift Imaging, to detect differences between the deep and superficial parts of the human leg muscles during dynamic knee extension exercise. The experiments were carried out with a 1.5-T superconducting magnet with a 5 inch-diameter circular sur-face coil. The subjects performed dynamic one-legged knee extension exercise in the prone position, with the transmit-receive coil placed under the right quadriceps muscles in the magnet. The subjects pulled down an elastic rubber band attached to the ankle at a frequency of 0.25, 0.5 and 1 Hz for 320 sec each. The Pi/PCr of the superficial parts was not significantly increased with increasing work rate. Compared with the superficial areas, the Pi/PCr of the deep parts was significantly higher (p < 0.05) at 1Hz. The intracellular pH showed no significant difference between the two parts.

Free Research Field

筋エネルギー代謝