Effect of folic acid and folic acid-containing foods against oxidative damage of human vascular endothelial cells

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500956
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits, studies on eating habits
• Research Institution: Doshisha Women's College of Liberal Arts
• Principal Investigator: MURAKAMI Megumi 同志社女子大学, 生活科学部, 准教授 (80340769)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 葉酸 / 抗酸化性 / 血栓溶解性 / ヒトさい帯静脈血管内皮細胞 / アスパラガス

Outline of Final Research Achievements

Standards of folic acid has been shown to have antioxidant properties, folic acid contained in foods was also revealed to have similar anti-oxidative properties. Its antioxidant is to be exerted against oxidative damage of vascular endothelial cells was suggested, the effect was weak.
In terms of stroke prevention, we examined the thrombolytic properties of folic acid using the fibrin plate method is a thrombosis model. As a result, were observed thrombolytic the standards of folic acid. However, thrombolytic was observed in folic acid that is extracted from asparagus. Thus, may show some effect on thrombus folic acid contained in the food has been suggested.

Free Research Field

調理科学