2016 Fiscal Year Final Research Report
Study on medicinal effects or clinical condition by simultaneous intake of functional food ingredients and drugs
| Project/Area Number |
24501027
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Fukuoka Institute of Technology |
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Principal Investigator |
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| Research Collaborator |
KOBA Kazunori
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| Project Period (FY) |
2012-04-01 – 2017-03-31
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| Keywords | 健康と食生活 / 機能性食品 / 安心・安全な利用法 |
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| Outline of Final Research Achievements |
We examine the influence on the medicinal effect or clinical condition of the simultaneous intake of functional food ingredients and drugs. First, we investigated the combination of antihypertensive drug and sardine peptide in spontaneously hypertensive rats. Because both of them have antihypertensive action by ACE inhibition. As a result, we could not find any alteration on the medicinal effect and clinical condition by the simultaneous intake of drug and functional food ingredients with similar mechanism of action. In addition, we examine the influence of medium-chain fatty acid on clinical condition in the type 1 and 2 diabetes animal models. Interestingly, in the type 1 animal models, we did not find the significant increase of blood ketone body and observed the survival advantage by the intake of medium-chain fatty acid compared with commercially available dietary oil.
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| Free Research Field |
栄養化学
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