Establishment of a protocol to examine the effects of endocrine disrupting chemicals on anuran metamorphosis.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24510083
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Risk sciences of radiation/Chemicals
• Research Institution: Hiroshima University
• Principal Investigator: SUZUKI Ken-ichi 広島大学, 理学(系)研究科(研究院), 特任講師 (90363043)
• Research Collaborator: KASHIWAGI Akihiko 広島大学, 大学院理学研究科, 特任教授 (50106796)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 甲状腺ホルモン / 変態 / 無尾両生類 / ツメガエル / 甲状腺ホルモン受容体

Outline of Final Research Achievements

The purpose of this research is to establish a new protocol to examine the effects of endocrine disrupting chemicals on anuran metamorphosis. Focusing on the molecular mechanism by which endocrine disruptors disturb metamorphosis, we tried to develop reporter transgenic lines and to analyze metamorphosis-related genes in Xenopus laevis and Xenopus tropicalis.

Free Research Field

内分泌かく乱