Electrophoretic Designer Polyesters and Application for Bone-Regeneration Scaffold

2014 Fiscal Year Final Research Report

• Project/Area Number: 24550132
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Polymer chemistry
• Research Institution: Nagoya Institute of Technology
• Principal Investigator: TAKASU AKINORI 名古屋工業大学, 工学(系)研究科(研究院), 教授 (30303697)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 電気泳動堆積(EPD) / ポリ(エステル-スルホン) / 非イオン性高分子 / 生体活性ガラス / 光触媒 / コーティング / ポリ(2-オキサゾリン)

Outline of Final Research Achievements

A room temperature thiol-ene click polymerization afforded a poly(ester-sulfide), which represents the first in a new class of click polyesters. Subsequent Oxone oxidation of the poly(ester-sulfide) led to the corresponding poly(ester-sulfone), which had improved thermal stability in comparison with the parent poly(ester-sulfide). A bioactive glass/poly(ester-sulfone) composite could be deposited on a stainless-steel anode by electrophoretic deposition (EPD). Hydroxyapatite was found on the surface of electrophoretically deposited bioactive glass/poly(ester-sulfone) composites that had been immersed in simulated body fluid (SBF) for 2 weeks. This bioactive glass/poly(ester-sulfone) composite might therefore find use as a surface coating for implantable medical devices on which a hydroxyapatite layer can form post implantation to strengthen the interface between the implant and host bone.

Free Research Field

高分子化学