Development of the artificial enzyme using visible light with vitamin B12 derivatives and human serum albumin.

2014 Fiscal Year Final Research Report

• Project/Area Number: 24550191
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Chemistry related to living body
• Research Institution: Kyushu University
• Principal Investigator: MASUKO Takahiro 九州大学, 工学(系)研究科(研究院), 技術専門職員 (40457445)
• Co-Investigator(Renkei-kenkyūsha): HISAEDA Yoshio 九州大学, 大学院工学研究院, 教授 (70150498)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: ビタミンB12 / 触媒反応 / 金属酵素 / 光触媒 / バイオインスパイアード

Outline of Final Research Achievements

The organic halide used for a pesticide is left to soil and the groundwater at long time. These continue affecting the creature until it is decomposed. On the other hand, it is known that the dehalogenase of the naturally occurring vitamin B12-dependent enzyme does de-chlorination reaction of the tetrachloroethylene. In this study, I succeeded in the development of the artificial enzyme using visible light with vitamin B12 derivatives and human serum albumin in water catalytically.

Free Research Field

錯体化学