Supression of wall shear stress inside cerebral aneurysm at bifurcation of anterior cerebral artery by stent

2014 Fiscal Year Final Research Report

• Project/Area Number: 24560208
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: Chiba University (2014); Shibaura Institute of Technology (2012-2013)
• Principal Investigator: YAMAGUCHI RYUHEI 千葉大学, 工学(系)研究科(研究院), 研究員 (90103936)
• Co-Investigator(Kenkyū-buntansha): TANAKA Gaku 千葉大学, 大学院工学研究科, 准教授 (20292667)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 脳動脈瘤 / 分岐 / 壁せん断応力 / ステント / 血行力学

Outline of Final Research Achievements

The effect of a simple bare metal stent on repression of wall shear stress inside a model cerebral aneurysm was experimentally investigated by two dimensional particle image velocimetry in vitro. The flow model simulated a cerebral aneurysm induced at the apex of bifurcation between the anterior cerebral artery and the anterior communicating artery. Wall shear stress was investigated using both stented and non-stented models to assess the simple stent characteristics. The flow behavior inside the stented aneurysm sac was unusual and wall shear stress was much smaller inside the aneurysm sac. Stent placement effectively repressed the temporal and spatial variations, and the magnitude of wall shear stress. Hence, there is an effective possibility that would retard the progress of cerebral aneurysms by even simple stent.

Free Research Field

脳動脈瘤発生の抑制と破裂予知