An imaging system of human body gas for evaluation of disease screening using chemiluminescence

2014 Fiscal Year Final Research Report

• Project/Area Number: 24560512
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Measurement engineering
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: ARAKAWA Takahiro 東京医科歯科大学, 生体材料工学研究所, 講師 (50409637)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 計測工学 / イメージング / ガス計測 / 酵素 / バイオセンサ / 生体計測 / 生体ガス

Outline of Final Research Achievements

An ethanol sensing and imaging system in the gas phase has been developed for analysis of breath ethanol. This breath gas imaging system has been expected to be easy, rapid and painless approach for sampling from patients to diagnose diseases. The system provides the image of ethanol distribution as chemiluminescence (CL) on the enzyme-immobilized mesh. The spatio and temporal changes in CL generated by ethanol in exhaled breath after ethanol oral administration was detected by employing an electron multiplier CCD camera. Breath samples from volunteers with aldehyde hydrogenase 2 (ALDH2) (+) and (-) are detected and analyzed with the imaging system. This imaging system for the human odor and skin gas has been expected to be the safe and useful assessment for metabolism in the body.

Free Research Field

計測工学