Production of calcium phosphate on titanium from a simulated body fluid flowing in a confined space

2014 Fiscal Year Final Research Report

• Project/Area Number: 24560821
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Inorganic materials/Physical properties
• Research Institution: Niigata University
• Principal Investigator: KIMURA ISAO 新潟大学, 自然科学系, 教授 (00169921)
• Co-Investigator(Kenkyū-buntansha): TAGUCHI Yoshinari 新潟大学, 自然科学系, 准教授 (30293202)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: リン酸カルシウム / チタン / 疑似体液 / 流動

Outline of Final Research Achievements

A small reactor involving a confined space was fabricated, in which calcium phosphate (CaP) was produced on titanium by flowing a simulated body fluid (SBF). The mixing characteristics in the reactor were evaluated by the impulse response testing. The relationship between the intermittently flowing conditions of SBF and the CaP yield was discussed. The crystalline phase of the product was identified as calcium-deficient hydroxyapatite. It was found that dispersion intensity is useful as an evaluation index of mixing characteristics instead of dispersion number used in general. The production of CaP was accelerated at larger dispersion intensity more than static condition. The knowledge on the effects of the SBF composition was also obtained.

Free Research Field

工学