Fabrication and characterization of plasma-polymerized film/biomolecule interface and its application for biosensors

2014 Fiscal Year Final Research Report

• Project/Area Number: 24560965
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Biofunction/Bioprocess
• Research Institution: Shibaura Institute of Technology
• Principal Investigator: MUGURUMA Hitoshi 芝浦工業大学, 工学部, 教授 (20309719)
• Co-Investigator(Kenkyū-buntansha): KUDO Susumu 九州大学, 工学(系)研究科, 教授 (70306926)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: バイオセンサ / プラズマ重合 / カーボンナノチューブ / 細胞 / パターンニング

Outline of Final Research Achievements

We focus on bionanointerface composed by plasma-polymerized organic thin film and protein molecule as a target of bionanointerface research. The purpose is the structural analysis of ten nanometer thick bionanointerface composed by plasma-polymerized film and biomolecule and the investigation of the relationship between its structure and material/device characteristics, then, orientate boosting the ability and expressing the new functionality. This bionanointerface is importantly positioned at biomaterials and biosensors supporting medicine. We have achieved the following two matters. (1) The highly sensitive biosensor with electronically-type sorted single-walled carbon nanotube, plasma-polymerized film, and biomolecule is presented. (2) Patterning of endothelial cells and hepatic stellate cells by two step plasma polymerization processes is presented.

Free Research Field

バイオセンサ