2014 Fiscal Year Final Research Report
the mechanism of development regulated by the nucleocytoplasmic transport
| Project/Area Number |
24570215
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cell biology
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| Research Institution | 独立行政法人医薬基盤研究所 (2014)
Osaka University (2012-2013) |
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Principal Investigator |
YASUHARA Noriko 独立行政法人医薬基盤研究所, その他部局等, 研究員 (90423152)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAOKA Kastuyoshi 大阪大学, 大学院生命機能研究科, 助教 (90551044)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 核輸送 / 分化 / 発生 / ノックアウトマウス |
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| Outline of Final Research Achievements |
To clarify the mechanism of development regulated by the nucleocytoplasmic transport, we attempted to create a knockout mouse targeting importin alpha, a typical nuclear transport receptor, and succeeded in obtaining the hetero knockout lines, of which the phenotype is now under analysis.
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| Free Research Field |
細胞生物学
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